Research Achievements

Publications

  1. Peerwani G, Khan SM, Khan MD, Bashir F, Sheikh S, Ramsey DJ, Aijaz S, Samad Z, Malik R, Hanif B, Virani SS. Gender Differences in Clinical Outcomes After Percutaneous Coronary Intervention—Analysis of 15,106 Patients from the Cardiac Registry of Pakistan Database. The American Journal of Cardiology. 2023 Feb 1;188:61-7.
  2. Aijaz S, Peerwani G, Bugti A, Sheikh S, Mustaqeem M, Mal SB, Memon A, Khan G, Pathan A. Management and outcome of post-myocardial infarction ventricular septal rupture—A Low-Middle-Income Country Experience. Plos one. 2022 Oct 27;17(10):e0276615.
  3. Khoso AA, Soomro GH, Mal SB, Malik R, Hanif B, Khan R. Frequency, Risk Factors, and Outcome of Definite Stent Thrombosis: A Single-Center Experience. Cureus. 2022 Jul 25;14(7).
  4. Munir U, Khan R, Nazeer N, Akhter J, ul Hassan A, Hanif B. Frequency and Predictors of Radial Artery Occlusion in Patients Undergoing Percutaneous Coronary Intervention. Cureus. 2022 May 30;14(5).
  5. Sheikh S, Van Cleve W, Kumar V, Peerwani G, Aijaz S, Pathan A. Cases of acute coronary syndrome and presumed cardiac death prior to arrival at an urban tertiary care hospital in Pakistan during the COVID-19 pandemic. Plos one. 2022 Feb 3;17(2):e0263607.
  6. Iqbal AM, Jamal SF, Ahmed A, Khan H, Khan W, Ahmed F, Santosh R, Ghazni MS, Mubarik A, Hanif B. Impact of Delayed Pain to Needle and Variable Door to Needle Time On In-Hospital Complications in Patients With ST-Elevation Myocardial Infarction Who Underwent Thrombolysis: A Single-Center Experience. Cureus. 2022 Jan 13;14(1).
  7. Aijaz S, Sheikh S, Pathan A. Combination of InnoSEAL plus TR band compared with TR band alone for radial artery outcomes in patients undergoing transradial coronary intervention (InnoSEAL-II): an open-label randomised controlled trial (protocol). BMJ open. 2020 Dec 1;10(12):e042101.
  8. Aijaz S, Ghazni MS, Malik R, Pathan A. Frequency and factors related to not receiving acute reperfusion therapy in patients with ST elevation myocardial infarction; a single specialty cardiac center. JPMA. 2019;69(1312)
  9. Aijaz S, Rind IA, Malik R, Akhter Z, Sattar S, Pathan A. In-hospital management and intermediate term outcomes in stable patients with ST segment elevation myocardial infarction presenting between 12-48 hours of symptom onset versus 2-7 days after the onset of chest pain; a single center study. JPMA. 2019;69(1657)
  10. Ghazni MS, Aijaz S, Malik R, Pathan AZ. Prevalence of non-acute ischaemic cardiomyopathy in a Pakistani cohort. Heart Asia. 2019;11(1):e011043.
  11. Sattar S, Ahmed N, Akhter Z, Aijaz S, Lakhani S, Malik R, Pathan A. In-Hospital outcomes in acute coronary syndrome patients with concomitant severe chronic kidney disease undergoing Percutaneous coronary intervention. Pakistan journal of medical sciences. 2019;35(2):291.
  12. Sattar S, Aijaz S, Akhter Z, Kim C, Lee MS, Malik R, Pathan A. comparison of two radial hemostasis techniques, catechol conjugated chitosan-based pad (innoseal) with compression band: a randomized controlled trial. Journal of the American College of Cardiology. 2019;73(9 Supplement 1):1391.
  13. Akhter Z, Hussain S, Aijaz S, Sattar S, Pathan A. Mortality and deciding factors for no revascularization in cardiogenic shock patients; a cross sectional study. JPMA. The Journal of the Pakistan Medical Association. 2019 Nov;69(11):1663-7.
  14. Akhter Z, Rind IA, Aijaz S, Sattar S, Malik R, Pathan A. Management, hospital outcome and revascularization trends in non-ST elevation myocardial infarction with high GRACE risk score. JPMA. The Journal of the Pakistan Medical Association. 2019 Oct 1;69(10):1486.
  15. Mangi S, Malik R, Lakhani M, Pathan A. Incidence and Outcome of Cardiogenic Shock Patients in a Pakistani Population: A-059. Catheterization and Cardiovascular Interventions. 2016 Apr;87.
  16. Shaikh AH, Hanif B, Pathan A, Hashmani S, Raza M, Khan W, Hussain SM, Hussain SM, Nasir S. Transradial primary percutaneous coronary intervention—experience from a tertiary care cardiac centre. Hypertension. 2013 Jun 1;107:66.
  17. Shaikh AH, Hanif B, Pathan A, Khan W, Hashmani S, Raza M, Nasir S. Primary Percutaneous Coronary Intervention for ST elevation myocardial infarction complicated by Cardiogenic Shock. J Pak Med Assoc. 2013 Apr 1;63:490-4.
  18. Factors affecting outpatient cardiac rehabilitation attendance after acute myocardial infarction and coronary revascularization – a local experience. M. Ali, Faisal Qadir, Salman Javed, Z.N.Khan, Sidra Asad, Bashir Hanif, J Pak Med Assoc April 2012:59:347-349.
  19. Correlation of Duke treadmill score with gated single photon emission computed tomography-myocardial perfusion imaging (SPECT-MPI) in patients referred for chest pain evaluation. Ayaz Hussain Shaikh, Bashir Hanif, Khursheed Hasan. J Pak Med Assoc April 2012:62:723-726.
  20. ASHRAF T, SULTANA R, TALPUR LC, RASOOL SI, PATHAN A, KUNDI A, ISHAQ M, ZAMAN K, FARUQUI A, MASOOD A. THE FREQUENCY OF HBV, HCV AND HIV IN PATIENTS UNDERGOING PERCUTANEOUS MITRAL VALVULOPLASTY. Pakistan Heart Journal. 2012 Nov 5;38(1-2).
  21. Coronary artery disease in patients undergoing valve replacement at a tertiary care cardiac centre.Ayaz Hussain Shaikh, Bashir Hanif, Khursheed Hasan, Amna Adil, Shahrukh Hashmani, Mohsin Raza, HA Qazi, Iqbal Mujtaba. J Pak Med Assoc April 2011:61:340-342
  22. Supracristal Ventricular Septal Defect with Severe Right Coronary Cusp Prolapse-A Case Report. Ayaz Hussain Shaikh, Bashir Hanif, Ghufranullah Khan, Khursheed Hasan. J Pak Med Assoc June 2011:61:605-607.
  23. Correlation of TIMI risk score with extent of coronary artery disease in patients with acute coronary syndrome. S. Lakhani, Faisal Qadir, Bashir Hanif, Salman Farooq, Moinuddin Khan. J Pak Med Assoc March 2010:60:197-200.
  24. Association of ST segment depression >5 min after exercise testing with severity of coronary artery disease. Ayaz Hussain Shaikh, Bashir Hanif, Adeel M Siddiqui, HunainaShahab, HA Qazi, Iqbal Mujtaba. J Pak Med Assoc April 2010:60(4):288-90.
  25. Doppler derived gradient of St Jude Mechanical Prosthesis – Early postoperative assessment.Ayaz Hussain Shaikh, Bashir Hanif, Amina Adil, Shahrukh Hashmi, H.A. Qazi, IqbalMujtaba. J Pak Med Assoc May 2010:60:374-376.
  26. Correlation of cardiac Troponin I levels (10 folds upper limit of normal) and extent of coronary artery disease in Non – ST elevation myocardial infarction. Faisal Qadir, Salman Farooq, Moinuddin Khan, Bashir Hanif, M.S. Lakhani. J Pak Med Assoc June 2010:60:423-428.
  27. Cholesterol emboli syndrome- A rare complication of cardiac catheterization.Ayaz Hussain Shaikh, Bashir Hanif, Khursheed Hasan., Faiza Malik. J Pak Med Assoc June 2010:60:492-94.
  28. Procedure Indications and outcome of percutaneous coronary interventions in a tertiary care hospital. Muhammad Shamim Siddique, Ayaz H. Shaikh, Bashir Hanif, Hammad Ali, S.M. F. Hussain, Sahr Sami, Mehreen Khan. J Pak Med Assoc July 2010:60:523-27.
  29. Safety and success of transradial coronary angiography and angioplasty in a Pakistani population. Moin Khan, Bashir Hanif – J Pak Med Assoc October 2010:61:809-813.
  30. Initial results of patient APT registry (1 month outcome of 50 patients) – Hanif B, Khan. M, Ahmed F., Soomro, K. Presented at GISSI, Genoa Itlay – December 2006
  31. Short and medium term outcome of Trapedilcoated Intrepide stent. – Hanif B, Khan. M, Ahmed F., Soomro, K Presented at CRT, Washington USA – March 2007
  32. Medium term outcomes of patient APT study. – Hanif B, Khan. M, Ahmed F., Soomro, K.Presented at Irish Cardiac Society Meeting, Dublin Ireland – October 2007
  33. Ashraf T, Pathan A, Memon A, Rasool I, Kundi A. Percutaneous balloon pericardiotomy in a patient with advanced case of malignant pericardial effusion and tamponade. JPMA. The Journal of the Pakistan Medical Association. 2008 Jun 1;58(6):335.
  34. Medium term outcome in diabetic and non diabetic patients in patient APT study. Hanif B, Khan. M, Ahmed F., Soomro, K Presented at CRT, Washington USA – February 2008
  35. Ayaz Hussain Shaikh, Ghufranullah Khan, Bashir Hanif, Faiza Malik, AtifBashirJColl Physicians Surg Pak Oct 2008;18(10):639-40.
  36. Non-STEMI caused by dual coronary emboli in a patient with atrial fibrillation. Hanif, B. Qadir, F. Hassan, K. Presented at Singapore Live 2008 Conference  (17th Annual Live Interventions in Vascular Endotherapy)
  37. Severe native aortic valve endocarditis and aortic abscess in a patient after abortion – Hanif, B. Qadir, F. Hassan. Presented at Singapore Live 2008 Conference  (17th Annual Live Interventions in Vascular Endotherapy)
  38. Chronic total left main coronary artery occlusion. Ayaz Hussain Shaikh, Bashir Hanif, Muhammad Adnan Amin, Faiza Malik J Pak Med Assoc Jan 2009(1):59:49-51.
  39. Chronic thromboembolic pulmonary hypertension. Ayaz Hussain Shaikh, Bashir Hanif, Faiza Malik, Atif BashirJ Pak Med Assoc May 2009; 59(5):323-5.
  40. Outcomes of primary Percutaneous Coronary Intervention (PCI) in a Tertiary Care Cardiac Centre. Ayaz Hussain Shaikh, Bashir Hanif, Muhammad Shamim Siddiqui, FaizaMalik,Khursheed Hasan,FatimaAdhi. J Pak Med Assoc. July 2009;59(7):426-9.
  41. Role of serum troponin I in identifying left ventricular ejection fraction of ≤ 40%in patients with acute anterior ST elevation myocardial infarction. Ayaz Hussain Shaikh, Bashir Hanif, Muhammad Shakir Lakhani, Faiza Malik J Coll Physicians Surg Pak, Sep 2009;19:544-547.
  42. Shaikh AH, Pathan A, Hasan K, Malik F, Qazi HA, Mujtaba I. Primary percutaneous coronary aspiration of thrombus from infarct related artery. J Coll Physicians Surg Pak. 2009 Dec 1;19(December (12)):791-3.

 

Research Grants & Collaborations

  • World Heart Federation (WHF): WHF COVID-19 and Cardiovascular Disease Survey
  • ABBOTT: To compare the time of occlusion of artery calculated from patient’s symptoms onset versus biochemical onset time in STEMI population using hsTnI
  • PHARMEVO:  Rivaroxaban- Does the pharmacokinetics of the less expensive brand match to the standard brand in patients with non valvular atrial fibrillation? A non-inferiority trial
  • INNOTHERAPY Comparison of two radial hemostasis techniques, catechol conjugated chitosan-based pad (InnoSEAL) with compression band; a randomized controlled trial (InnoSEAL I). InnoSEAL+TRB is non-inferior to TRB alone in terms of the composite adverse access site outcomes including RAO and hematoma
  • Anti-Coronavirus Therapies (ACT) to prevent progression of COVID-19: Randomized trials. Sponsored by Hamilton Sciences through Population Health Research Institute (PHRI).
  • INNOTHERAPY: Low dose versus high dose heparin with or without hemostasis patch and radial access site outcomes; an open-label factorial trial (InnoSEAL III) PI: Asad Pathan
  • Medtronic: Prediction of surgical valve type selection using data on long-term clinical outcomes and quality of life among patients with mechanical and bio-prosthetic surgical heart valve replacement in a Lower Middle-Income country PI: Asad Pathan
  • Getzpharma: PAKistan Study of prEmature coronary atHerosclerosis in young AdulTs (PAK-SEHAT) PI: Bashir Hanif
  • Medtronic: Recurrent atrial fibrillation in post-operative atrial fibrillation PI: Fariha Sadiq
  • NHS-Islamabad: A phase II trial on first locally manufactured drug-eluting stent PI: Bashir Hanif
  • World Heart Federation: Long COVID-19 and Cardiovascular Disease Survey PI: Sana Sheikh
  • American College of Cardiology: Global Heart Attack Treatment Initiative (GHATI) PI: Bashir Hanif
  • Institute of Business Administration: Customized consent form for CABG patients based on the patients’ risk of morbidity and mortality PI: Asad Pathan

Abstract Presentations

  1. Predictors associated with 30-day mortality in 2,155 patients undergoing valve replacement surgery in a low-to-middle-income country. American College of Cardiology Conference-2022
  2. Stages of chronic kidney disease and post-PCI in-hospital mortality among 6,884 patients entire spectrum of coronary artery disease presentation. American College of Cardiology Conference-2022
  3. Risk profile and outcomes of patients with premature and extremely premature coronary artery disease compared with older adults: Analysis of the cardiac registry of Pakistan (CROP) database. American College of Cardiology Conference-2022
  4. Predictors of 1-year mortality in 6656 chronic kidney disease patients across the entire spectrum of coronary artery disease. Society for Cardiovascular Angiography and Interventions (SCAI)-2022
  5. Sex differences in immediate outcomes of young ST-elevation myocardial infarction (STEMI) patients-Insights from a single-center registry of a Low-Middle-Income-Country. American Society of Preventive Cardiology-2022
  6. Presentation, Management, and early outcomes of young acute coronary syndrome patients- Analysis of 23,560 South Asian patients from 2012-2021. American Society of Preventive Cardiology-2022